Perineuritis: Positive staining cells in perineurium; Endoneurial cells reflect Wallerian...Phagocytes (vacuolated) in endoneurium Large cells: Contain myelin debris or round, clear lipid...Acid phosphatase stain Phagocytic cells, EndoneurialPhagocytes (vacuolated) in endoneurium Large cells: Contain myelin debris or round, clear lipid...Figure 2. Physiological and morphological evidence for preservation of axons and neuromuscular...Confluent red stained cells,probably macrophages, mainly in perineurium.Figure 3. Dose-dependence of axon protection by the Wld gene. ( a ) Top, western blot showing the...Cerebral infarctions can be accompanied by Walleriandegeneration of descending tracts, as shown...Waller Walleriandegeneration: Principles & Features Walleriandegeneration: Definition Sequence of...Waller Walleriandegeneration: Principles & Features Walleriandegeneration: Definition Sequence of...Figure 4. Axon protection 10−14 days after transection. ( a ) Western blot showing the extent of...Figure 6. NAD + metabolism in Wld S brain. ( a ) Increased Nmnat activity and ( b ) unaltered NAD +...Axon & Myelin: Degeneration & LossGomori trichrome stain Myelinated axons: Reduced numbersSupplementary Figure 2 ( jpg 1.2MB) The transgene construct and evidence for genomic integration. (...Toluidine blue stainFigure 11. The cerebral angiogram of an 87-year-old man with acute onset left hemiplegia. The right...Supplementary Figure 3 ( jpg 337K) Wld protein is not detectable in axons of sciatic nerve ( a )...Supplementary Figure 1 ( jpg 223K) Higher magnification of preserved axon ultrastructure in distal...Definition of nerve injury: The mildest grade is called neurapraxia. Neurapraxia is a reduction or...Figure 2.